Archive for the ‘Research’ Category

Frannie
Marmorstein

Lupus Advocates Take On the Hill

Tuesday, March 29th, 2011

Last week I had the opportunity to participate in the Lupus Research Institute’s Tell Congress Event on Captiol Hill. Lupus is an autoimmune disorder with an unknown cause that affects the skin, joints, kidneys and other organs and involves the immune system attacking healthy cells and tissue because it cannot tell the difference between normal and unhealthy substances.

I spent the afternoon lobbying on the Hill with a dozen Lupus advocates, meeting with senators and listening as advocates voiced their concerns about Lupus awareness and increasing funding for lupus research. Advocates strived to make an impact by sharing with their senators their personal connections with the disease. Patients shared their difficulties living with chronic fatigue and joint pain, family members honored those they had lost to Lupus and caregivers, including children, discussed the hardship of caring for a parent with Lupus. Everyone had a story to share.

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Frannie
Marmorstein

Fountain of Youth Discovered?

Tuesday, November 30th, 2010

The reversal of aging has been a recurring theme in fictional movies, books, and television shows, but is there a possibility that this fiction could become a reality? Remember Benjamin Button, Mork and Mindy, Tuck Everlasting and Twilight?

A colleague of mine passed along an interesting article yesterday; a group of researchers at Harvard-affiliated medical centers have partially reversed the aging process in mice. The mice were genetically manipulated to age faster, and then treated with gene therapy to lengthen telomeres — compounds found at the ends of strands of DNA — which reversed age-related problems such as decreased brain function and infertility.

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Harold
Silverman

Top 5 Challenges of Biosimilars

Tuesday, October 26th, 2010

syringe_glove_01The Food and Drug Administration is wrestling with how to best implement the Biologics Price Competition and Innovation Act. The agency is writing regulations that will set the exact rules for gaining biosimilar approval and has scheduled a meeting to obtain public input on the regulatory pathway that is being considered. The meeting is set for November 2-3 and will be held at FDA’s facility in Silver Spring, Maryland. The full meeting announcement can be found here. A live webcast of the 2-day event can be found here.

A quick look at some of the issues the FDA wants input on during the hearing shows how different biosimilars are from traditional generic regulation. Besides those discussed below, the FDA is seeking comment on a variety of marketing, technical and regulatory issues. The breadth and depth of all these questions speak to the complexities of the issues that are being dealt with. Given the uncertainty surrounding pending decisions and their impact on companies seeking to enter the biosimilar market, I believe the first U.S. biosimilar will not to be approved for at least two years.

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Megan
Lustig

Inspiration for Rutgers’ Eric LeGrand: Because Impossible is only a Word, Not a Reality

Tuesday, October 19th, 2010

nothingis1As the wife of a current collegiate football coach who played in college, I know that there are few words to express the emotions surrounding Rutgers’ defensive tackle Eric LeGrand’s horrific injury this weekend. My heart goes out to Eric’s family and the Rutgers community – I sat through so many games when if my husband (boyfriend at the time) even slightly hesitated after a hit, I panicked, and yet the worst he suffered was a broken leg. In Kieran Darcy’s ESPN article about the incident, he quotes Rutgers’ head coach Greg Schiano:

“Eric, his family and the Rutgers football family believe he will recover,” said Rutgers coach Greg Schiano. “We ask our fans and the entire Rutgers community to believe and pray for Eric as he begins the recovery process.”

For many football fans, this may bring back memories of the injuries sustained by Penn State cornerback Adam Taliaferro, or Buffalo Bills player Kevin Everett. Adam and Kevin, however, are back on their feet.

People may have varying opinions on the attributes of a successful athlete, but it is hard to deny that discipline, dedication, and a tremendous work ethic are at the core of what it takes to succeed. So when athletes face the life-altering challenge of paralysis, they depend on these attributes when faced with a completely new, unexpected training regimen. Because of Eric’s accident, I would like to offer the story of Matt Courson as a source of inspiration for Eric, the Rutgers community, and anyone else affected by paralysis. According to Matt, impossible is only a word, not a reality.

Matt Courson’s story is one of an inspirational and motivated All-State selection, 8AAA Pitcher of the Year, and collegiate pitcher who has faced the same life-altering challenge as Eric – paralysis. Yet Matt’s story is about more than his dedication and remarkable recovery. His outlook on life burns so bright that everyone he meets is taken with him, and he says that when he speaks and people tell him that they were helped by his story, “it is better than any strike-out, bigger than any baseball game you can play.” And what is phenomenal, is that when Matt graduates from college this Spring, he will get out of his wheelchair, and walk across the stage.

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Spectrum

Technology Tuesday: Empowering the Research Enterprise in a Post-Reform World

Tuesday, April 6th, 2010

With the passage of health care reform, the research community is ready to shift the national health policy conversation to a new dialogue on enhancing biomedical research and scientific innovation. In the past few weeks, discussion on topics such as the need to improve the translation of research discoveries into better health outcomes and the research ROI  for improving the nation’s overall health have gained traction alongside continued analysis of the final health reform provisions.

At the recent Research!America National Forum, experts from across the government, industry, academia and patient advocacy sectors discussed priorities to speed translational research, improve health outcomes and ultimately, as panelist Dr. Robert Tijian, president of the Howard Hughes Medical Institute put it, identify new pathways to “move beyond therapeutics and treatment to prevention.”  Yet transformation of this level requires a deep commitment to enhancing cross stakeholder collaborations and sustained communication, a challenge with so many players involved in the research process.innovation-technology
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John
Seng

The Dr. Oz Show To Bring Mass Exposure To Rare Disease

Wednesday, February 24th, 2010

Yesterday, we accompanied our pro bono client, The Progeria Research Foundation (PRF), to a taping of The Dr. Oz Show at NBC Studios in New York. You know, 30 Rock.

(l-r), Genetics Expert Jeffrey Innis, MD, PhD, Mott Children’s Hospital, University of Michigan; Television’s Dr. Oz; John Seng, President, Spectrum

(From left to right) Genetics Expert Jeffrey Innis, MD, PhD, Mott Children’s Hospital, University of Michigan; Television’s Dr. Oz; John Seng, President, Spectrum

Spectrum has worked closely with PRF since 2003 to raise awareness of Progeria, a rare, and thus far incurable disease that causes rapid aging among children. Most children live no longer than 20 years. (more…)

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