Posts Tagged ‘Vaccine’

Ali
Martin

Week-Long Immunization Campaign Reaches Millions

Thursday, June 3rd, 2010

FACT: An estimated 10 million cases and 164,000 deaths from measles occur each year.

FACT: Measles is a leading cause of vaccine-preventable deaths among young children.

FACT: For every 1,000 children who get measles, one or two will die.

When I came across these chilling statics from the Centers for Disease Control and Prevention (CDC), I was surprised by the incidence rate and the severity of a disease that we in the U.S. rarely see. In developing countries, measles is a killer, so I was interested to learn about a program underway in Zimbabwe.

Image Courtesy of WHO

Image Courtesy of WHO

Last week, Dr. Henry Madzorera, Zimbabwe's Honorable Minister of Health and Child Welfare, launched a week-long nationwide measles immunization campaign. The "Child Health Days" campaign targeted approximately 5 million children aged 6 months to 14 years with the measles vaccination, as well as vitamin A supplementation and all the other recommended antigens for children less than five years of age. This mass immunization campaign came in response to the current measles outbreak that has affected 55 out of 62 districts in Zimbabwe, killing approximately 384 children. (more...)

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Maggie
Schmerin

Britain Bans Doctor Who First Linked MMR Vaccine to Autism

Thursday, May 27th, 2010

Earlier this week, Great Britain banned Andrew Wakefield, the doctor who first linked the measles, mumps and rubella (MMR) vaccine to autism, from practicing medicine in the U.K.Britain's General Medical Council said Dr. Wakefield and two other doctors acted unethically and showed a "callous disregard" for the children in their study on autism and vaccines that was first published in The Lancet in 1998. The medical body said Dr. Wakefield took blood samples from children at his son's birthday party, paying them 5 pounds (roughly $7.20 today) each and later joked about the incident. The General Medical Council said Wakefield abused his position as a doctor and "brought the medical profession into disrepute."

Dr. Wakefield's claims of a relationship between the MMR vaccine and autism prompted parents around the globe to not only question vaccinating their children, but also caused millions to forgo vaccinating their young ones all together. Immunization rates in the U.K. and other developed countries have noticeably decreased since Dr. Wakefield's article was first published over a decade ago. Outbreaks of the measles have continued in Europe, and there are still intermittent outbreaks in the U.S.  (more...)

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Maggie
Schmerin

Spectrum Infection: Lessons Learned - H1N1 A Year Later

Tuesday, April 20th, 2010

nicGreetings from the 44th National Immunization Conference in Atlanta! With the one year anniversary of the H1N1 outbreak upon us this week, there is not a more fitting place for officials from NIH, HHS, CDC, FDA, state and local health agencies, vaccine advocacy organizations and vaccine manufacturers to gather.

Department of Health and Human Services (HHS) Secretary Kathleen Sebelius delivered the conference's keynote address, which focused on the response to the H1N1 flu pandemic, the lessons learned and efforts to strengthen America's health security in the future.

On April 21, 2009, the CDC was alerted to a new strain of influenza in California and Texas, similar to one that was presenting in Mexico. Kathleen Sebelius was still serving as governor of Kansas, but seven short days later would be sworn in as our country's 21st HHS Secretary and quickly whisked into the Situation Room at the White House where President Obama and other government leaders were beginning to mount an attack on what would become the world's first pandemic in 40 years.

Over the course of the past 12 months, the federal government worked alongside state and local health agencies to ensure that Americans were prepared for and protected against H1N1, and the H1N1 vaccine was the keystone of these efforts. As Secretary Sebelius stated, "The H1N1 vaccine was the most ambitious immunization campaign ever." (more...)

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Brennan
Gamwell

Spectrum Infection Thursday: April Marks STD Awareness Month in the United States

Thursday, April 15th, 2010

stdawarelogo2April doesn't just mark the beginning of allergy season.  In fact, April also marks STD Awareness Month in the United States, an annual observance designed to raise awareness of sexually transmitted diseases and the importance of testing and prevention for long-term health.  There is perhaps no better time to begin discussions of developments in sexual wellness and care, especially concerning HPV-one of the most widespread sexually transmitted infections out there.  To give you some sense of the urgency surrounding the relative ubiquity of HPV, I want to give you a quantitative view of the problem: between 50 and 70 percent of sexually active adults will contract some strain of the HPV virus in their lifetime.

In light of these statistics, last year Merck sought FDA approval to market and administer the HPV vaccine Gardasil to boys and men, ages 9 to 26.  The FDA approved the use of the vaccine, and now questions have begun to arise as to whether boys and men should indeed receive the vaccine on a large scale.  Moreover, according to the CDC's Web site, there is currently no test to screen for HPV in males, so preventive measures become even more valuable-for a variety of reasons. 

While women can be tested for HPV infections as part of a routine screening for cervical cancer, men face a greater challenge detecting and receiving pre-malignant treatment for the disease.  HPV undeniably causes a high incidence of cervical cancer if left untreated-which has been well-documented by both health professionals and the media-but it can also spur the growth of invasive forms of anal and penile cancers, which are often deadly if not treated early.  Lower incidence of undetectable HPV infection in males curtailed by vaccination therefore translates into a lower transmission rate to sexual partners, as well as a lower incidence of aggressive cancers in males later in life. (more...)

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Katharine
Perrow

The Results Are In: WHO and CDC Release Data on the 2009 Swine Flu

Monday, February 22nd, 2010

Last year there was not enough time to include the H1N1 strain in the formulation for the annual seasonal flu vaccine, but this year will be different. After its four-day influenza meeting, the World Health Organization (WHO) has recommended that the 2010 seasonal flu vaccine contain protection from the swine flu.  

Despite the fact that experts believe a third wave in the spring is an improbability, the WHO expects swine flu to remain a significant threat in the years ahead. The WHO plans to discuss this third wave probability during another official meeting, set to take place next week. Is this season's H1N1 pandemic officially over? We'll have to wait and see what comes out of the meeting.

From the field, we're hearing that doctors and clinics throughout the U.S. are reporting a decrease in the typical number of seasonal flu cases. Cases of swine flu, and similar conditions such as RSV, which primarily affects small children, have now surpassed those of seasonal flu patients. Public health officials are slightly puzzled by this. Perhaps more will come to light after we've become accustomed to H1N1 as an official part of the influenza conversation. (more...)

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Michael
Cover

This Morning We Discovered Hope

Thursday, September 24th, 2009

This morning I woke up to news I have been waiting to hear for more than 20 years.  Researchers have finally developed a preventive vaccine against HIV that showed modest efficacy.  For every 100 people that would have become infected if they had not received the vaccine, 32 infections were prevented.  This level of efficacy (32%) is modest, and too low to proceed to license the vaccine.  However, the results are significant.  They will give a real boost to the field and provide a base on which they can improve.

While this is absolutely reason to celebrate a remarkable scientific achievement, we should note a couple of important things:

First, the vaccine was only studied with the type of HIV commonly found in Thailand.  More research will have to be done to discover whether similar results can be shown in Africa and North and South American strains.

Second, researchers also wanted to discover if the vaccine had any effect on reducing the amount of virus in the blood of volunteers who seroconverted during the trial.  Sadly, it did not have any therapeutic benefits.

Still, this is a clear victory that gives researchers, and all of us who care about ending AIDS, one thing that has been in short supply:  hope that we will be the generation that ends AIDS through the discovery of a preventive vaccine.

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